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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
26.67
Human Site:
Y232
Identified Species:
48.89
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
Y232
K
I
R
G
G
V
F
Y
I
P
E
Y
L
N
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
Y234
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Dog
Lupus familis
XP_546691
722
81319
Y402
K
I
R
G
G
V
F
Y
I
P
E
Y
L
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
Y232
K
I
R
G
G
V
F
Y
I
P
D
Y
L
N
R
Rat
Rattus norvegicus
Q09137
552
62239
Y232
K
I
R
G
G
V
F
Y
I
P
E
Y
L
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
Y203
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Chicken
Gallus gallus
Q9IA88
798
88848
R241
R
V
L
E
G
R
F
R
I
P
Y
F
M
S
E
Frog
Xenopus laevis
NP_001088426
560
64038
Y243
K
I
C
D
G
I
F
Y
T
P
Q
Y
L
N
P
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
R274
R
V
L
S
G
K
F
R
I
P
F
F
M
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
I206
D
I
W
S
C
G
I
I
L
Y
A
L
L
C
G
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
P303
K
I
K
S
G
V
F
P
T
P
D
F
L
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
I229
D
V
W
S
C
G
V
I
L
Y
A
L
L
C
G
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
T270
N
I
S
N
G
V
Y
T
L
P
K
F
L
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
60
100
N.A.
93.3
100
N.A.
60
26.6
60
26.6
N.A.
N.A.
13.3
53.3
N.A.
P-Site Similarity:
100
N.A.
73.3
100
N.A.
100
100
N.A.
73.3
60
73.3
60
N.A.
N.A.
20
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% A
% Cys:
0
0
24
0
16
0
0
0
0
0
0
0
0
16
0
% C
% Asp:
16
0
0
24
0
0
0
0
0
0
16
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
24
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
77
0
0
0
8
31
0
0
0
% F
% Gly:
0
0
0
31
85
16
0
0
0
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
77
0
0
0
24
8
16
47
0
0
0
0
0
0
% I
% Lys:
62
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
16
0
0
0
0
0
24
0
0
16
85
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
0
54
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
85
0
0
0
0
31
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% Q
% Arg:
16
0
31
0
0
8
0
16
0
0
0
0
0
0
39
% R
% Ser:
0
0
8
31
0
0
0
0
0
0
0
0
0
24
0
% S
% Thr:
0
0
0
0
0
0
0
8
31
0
0
0
0
0
8
% T
% Val:
0
24
0
0
0
47
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
0
16
8
54
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _